My research concerns the development and application of genomics technologies to inform properties of human physiology, including the somatic changes in our cells. In particular, I am interested in studying the earliest events of tumor initiation (pre-malignant clonal expansions) and the immune cells within these tissues and tumors. My highly-collaborative research has recently been highlighted by Nature, Nature Methods, and the 10x Genomics Innovator Series.
July 2020 - Present
I currently hold appointments in the Department of Pathology and the Department of Genetics at Stanford University School of Medicine. As part of the inaugrual class of Stanford Science Fellows, I lead a semi-independent research program to study fundamental attributes of human tissues in health and disease. My research is supported by funding from the Parker Institute for Cancer Immunotherapy, and Stanford Medical School.
August 2015-June 2020
I completed my graduate studies at Harvard Medical School, where I earned my PhD in the Division of Medicine Sciences. My dissertation focusd on the development of new single-cell methods and technologies, particular the development of an approach to trace clonal lineages in human cells via somatic mtDNA mutations. My time at Harvard was split between the Broad Institute, Boston Children’s Hospital, and Dana Farber Cancer Institute.
Max Planck Institute
May 2013-August 2014
For two summers during my undergraduate training, I completed research projects at the Max Planck Institute for Psychiatry in Munich Germany, which was supported by a Deutscher Akademischer Austauschdienst RISE Fellowship. Here, I examined potential biomarkers in the blood that were associated with patient outcomes in response to deep brain stimulation, an investigative new therapy for treatment-resistant depression.
University of Tulsa
August 2011-May 2015
I completed my undergraduate education at the University of Tulsa where I graduate summa cum laude with a BSc in Biochemistry and Mathematics. Here, I performed research in the in silico Research Group, establishing computational methods for the network modeling of human genetic variation data.
Honors and Awards
- Parker Scholar, Parker Institute for Cancer Immunotherapy, 2021
- Stanford Science Fellow, Stanford University, 2020
- Ruth L. Kirschstein National Research Service Award (NCI F31), National Cancer Institute, 2018
- Graduate Research Fellowship, National Science Foundation, 2015
- Robertson Most Outstanding Senior, Pi Kappa Alpha, 2015
- Walter and Adelheid Hohenstein Fellowship, Phi Kappa Phi, 2015
- Jess Chouteau Outstanding Senior, University of Tulsa, 2014
- Goldwater Scholar, Barry M. Goldwater Foundation, 2013
- RISE Fellow, Deutscher Akademischer Austauschdienst, 2013, 2014
- Presidential Scholar, University of Tulsa, 2011
- Sir Alexander Fleming Scholar, Oklahoma Medical Research Foundation, 2011
In the News
- Hacking single-cell technologies to trace lineages in cancer
- 10x Genomics Innovator Series, August 2021
- An expanded arsenal of single-cell methods via DOGMA-seq
- Nature Methods, August 2021
- The ‘kitchen-seq’ of single-cell multiomics analyses
- Nature, July 2021
- A comprehensive map of how the SARS-CoV-2 RNA interacts with cells
- Science Daily, December 2020
- Accelerating single-cell research via droplet microfluidics
- Harvard Gazette, June 2019
- Unexpected mutations caused by CRISPR have a different explanation
- Forbes, July 2017